The IMPAACT HIV Complications & Co-morbidities Scientific Committee aims to determine optimal and feasible methods for the prevention and management of co-infections and co-morbidities of HIV infection and its treatment. Neurocognitive impairment, chronic immune activation/inflammation, serious HIV co-infections and toxicities of long-term ARV exposure are significant causes of disease in these vulnerable populations and need to be addressed to reduce and prevent serious morbidities. Priorities include evaluation of:
- Interventions to prevent or treat cognitive impairment and mood disorders in HIV-infected children.
- The importance of the inflammatory state characteristic of HIV infection in children during growth and development and evaluation of interventions to alter it and related complications.
- Signals of adverse events (AEs) occurring in HIV-infected children in long term follow-up as a result of HIV infection or treatment for HIV infection and its complications.
- Vaccines for infectious agents other than HIV that cause significant morbidity and/or mortality in HIV-exposed infants and HIV-infected pregnant women, children, and adolescents.
Committee ContactsChair: Allison Agwu
Vice-Chair: Mark Abzug
Operations Center: Jen Libous and Jackie Mountcastle
Presentations2016 IMPAACT Annual Meeting Complications & Comorbidities Scientific Committee presentations
Studies Within This Research Area