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Research Areas

HIV Complications & Co-Morbidities

The IMPAACT HIV Complications & Co-morbidities Scientific Committee aims to determine optimal and feasible methods for the prevention and management of co-infections and co-morbidities of HIV infection and its treatment. Neurocognitive impairment, chronic immune activation/inflammation, serious HIV co-infections and toxicities of long-term ARV exposure are significant causes of disease in these vulnerable populations and need to be addressed to reduce and prevent serious morbidities. Priorities include evaluation of:

  • Interventions to prevent or treat cognitive impairment and mood disorders in HIV-infected children.
  • The importance of the inflammatory state characteristic of HIV infection in children during growth and development and evaluation of interventions to alter it and related complications.
  • Signals of adverse events (AEs) occurring in HIV-infected children in long term follow-up as a result of HIV infection or treatment for HIV infection and its complications.
  • Vaccines for infectious agents other than HIV that cause significant morbidity and/or mortality in HIV-exposed infants and HIV-infected pregnant women, children, and adolescents.

Committee Contacts

Chair: Allison Agwu
Vice-Chair: Mark Abzug
Operations Center: Jen Libous

Presentations

2016 IMPAACT Annual Meeting Complications & Comorbidities Scientific Committee presentations

2015 IMPAACT Annual Meeting Complications & Comorbidities Scientific Committee presentation

Studies Within This Research Area

IMPAACT 2016
IMPAACT 2013
IMPAACT 2012
IMPAACT 2011
IMPAACT 2002
IMPAACT P1104s
IMPAACT P1080
IMPAACT P1076

 

 

 

 

 

 

 

 

 

 

 

Funded by the National Institute of Allergy and Infectious Diseases, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Institute of Mental Health of the US National Institutes of Health, US Department of Health and Human Services.