The IMPAACT Tuberculosis Scientific Committee aims to evaluate novel approaches for tuberculosis (TB) prevention, treatment and diagnosis in HIV-infected children, adolescents, and pregnant women. TB is a major cause of morbidity and mortality among HIV-infected pregnant women and children, and the diagnosis of TB in children is very difficult. Evaluation of new TB drugs and TB vaccines for PK, safety, dosing, and efficacy is lacking in these vulnerable populations as are accurate diagnostic tests for TB in children. Priorities include evaluation of:
- PK, safety and efficacy of new drugs and drug combinations to prevent and treat TB in HIV-infected and uninfected children, adolescents, and pregnant women.
- Novel strategies for diagnosing TB in HIV-infected and uninfected children.
- Novel vaccines for prevention of TB in HIV-infected and uninfected children.
Committee ContactsChair: Anneke Hesseling
Vice Chair: Amita Gupta
Operations Center: Sarah Bradford and Jackie Mountcastle
Presentations2016 IMPAACT Annual Meeting Tuberculosis Scientific Committee presentations
Studies Within This Research Area