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Research Areas

Tuberculosis

The IMPAACT Tuberculosis Scientific Committee aims to evaluate novel approaches for tuberculosis (TB) prevention, treatment and diagnosis in HIV-infected children, adolescents, and pregnant women. TB is a major cause of morbidity and mortality among HIV-infected pregnant women and children, and the diagnosis of TB in children is very difficult. Evaluation of new TB drugs and TB vaccines for PK, safety, dosing, and efficacy is lacking in these vulnerable populations as are accurate diagnostic tests for TB in children. Priorities include evaluation of:

  • PK, safety and efficacy of new drugs and drug combinations to prevent and treat TB in HIV-infected and uninfected children, adolescents, and pregnant women.
  • Novel strategies for diagnosing TB in HIV-infected and uninfected children.
  • Novel vaccines for prevention of TB in HIV-infected and uninfected children.

Committee Contacts

Chair: Anneke Hesseling
Vice Chair: Amita Gupta
Operations Center: Sarah Bradford, Patricia Morgan, and Nicole Montanez

Presentations

2016 IMPAACT Annual Meeting Tuberculosis Scientific Committee presentations

2015 IMPAACT Annual Meeting Tuberculosis Scientific Committee presentation

Studies Within This Research Area

IMPAACT 2005
IMPAACT 2003/2003B (PHOENIx)
IMPAACT 2001
IMPAACT P1113/AERAS 404
IMPAACT P1108
IMPAACT P1101
IMPAACT P1078

 

 

 

 

 

 

 

 

 

 

 

Funded by the National Institute of Allergy and Infectious Diseases, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Institute of Mental Health of the US National Institutes of Health, US Department of Health and Human Services.