IMPAACT 2002 (DAIDS ID 12051): Combined Cognitive Behavioral Therapy and a Medication Management Algorithm for Treatment of Depression among Youth Living with HIV in the United States

Study Status Study Restriction

Open to Accrual

United States

What is IMPAACT 2002?

IMPAACT 2002 is multi-site, two-arm, cluster-randomized study to examine if a Health and Wellness Cognitive Behavioral Therapy and Medication Management for depression improves outcomes for HIV-infected youth in the United States. Approximately 130 HIV-infected youth, ages 14-24 with depression, will be assigned to either Health and Wellness Cognitive Behavioral Therapy and Medication Management group or the Enhanced Standard of Care group and followed for 48 weeks. The study will examine whether participants receiving Health and Wellness Cognitive Behavioral Therapy and Medication Management Algorithm treatment for depression demonstrate improved depression outcomes and improved biological measures of health compared to participants receiving the Enhanced Standard of Care therapy.

Study Documents:

Study Training Materials:

Sites where the study is implemented:

CRS ID Site Name City Country

3801

Texas Childrens Hosp. CRS

Houston

United States of America

4601

UCSD Mother-Child-Adolescent HIV Program

San Diego

United States of America

5013

Jacobi Medical Center Bronx

Bronx

United States of America

5030

Emory University School of Medicine NICHD CRS

Atlanta

United States of America

5040

SUNY Stony Brook

Stony Brook

United States of America

5048

University of Southern California LA

Los Angeles

United States of America

5052

University of Colorado Denver NICHD CRS

Aurora

United States of America

5055

South Florida CDTC Ft Lauderdale NICHD CRS

Fort Lauderdale

United States of America

5083

Rush University Cook County Hospital Chicago NICHD CRS

Chicago

United States of America

5092

Johns Hopkins University, Baltimore

Baltimore

United States of America

5112

UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CR

Los Angeles

United States of America

5114

Bronx-Lebanon Hospital IMPAACT

Bronx

United States of America

6501

St. Jude/UTHSC CRS

Memphis

United States of America

Study contacts:

Study Chair: Larry Brown

Study Vice-Chair: Patricia Emmanuel

Study Vice-Chair: Beth Kennard

DAIDS Medical Officer: Adeola Adeyeye

DAIDS Medical Officer: Ellen Townley

NICHD Medical Officer: Sonia Lee

NIMH Medical Officer: Susannah Allison

Clinical Trials Specialist: JL Ariansen

Clinical Trials Specialist: Kathryn Lypen

CAB representative: Leslie Raneri

Community Program Manager: Cheryl Cokley

Data Manager: Jenna Kearly

Data Manager: Elise Tjaden

Immunologist: Adriana Weinberg

Investigator: Graham Emslie

Investigator: Taryn Mayes

Investigator: Laura Whiteley

Laboratory Data Manager (LDM): Laura Hovind

Laboratory Specialist: Diane Costello

Laboratory Technologist: William Kabat

Proposal Statistician: Miriam Chernoff

Statistician: Shirley Traite

Westat Representative: Rita Patel

 

Funded by the National Institute of Allergy and Infectious Diseases, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Institute of Mental Health of the US National Institutes of Health, US Department of Health and Human Services.