IMPAACT 2015: Evaluation of the HIV Reservoir in the Central Nervous System of Perinatally-Infected Youth and Young Adults with Neurocognitive Impairment

Study Status Study Restriction

In Development

United States

What is IMPAACT 2015?

IMPAACT 2015 is a cross-sectional study that will investigate the central nervous system reservoir in perinatally HIV-infected adolescents and young adults on effective antiretroviral therapy with neurocognitive impairment. The study will assess the frequency with which HIV is detected in the cerebral spinal fluid (CSF) in this population and assess whether detectable HIV in the CSF correlates with markers of inflammation and neuronal injury.

Sites where the study is implemented:

CRS ID Site Name City Country
Site Selection in progress.

Study contacts:

Study Co-Chair: Ann Chahroudi

Study Co-Chair: Thor Wagner

DAIDS Medical Officer: Elizabeth (Betsy) Smith

NICHD Medical Officer: Eric Lorenzo

NIMH Medical Officer: Jeymohan Joseph

Clinical Trials Specialist: Anne Coletti

Community Program Manager: Rhonda White

DAIDS Protocol Pharmacist: Lynette Purdue

Data Manager: Kayla Denson

Data Manager: Amanda Golner

Data Manager: Chelsea Krotje

Investigator: Jintanat Ananworanich

Investigator: Kathleen Malee

Investigator: Sharon Nichols

Investigator: Deborah Persaud

Investigator: Stephen Spector

Investigator: Serena Spudich

Investigator: Lydie Trauttman

Investigator: Russell Van Dyke

Laboratory Data Manager (LDM): Kaitley Wozer

Laboratory Specialist: Diane Costello

Laboratory Technologist: Paul Harding

Statistician: Konstantia Angelidou

Westat Representative: Rita Patel


Funded by the National Institute of Allergy and Infectious Diseases, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Institute of Mental Health of the US National Institutes of Health, US Department of Health and Human Services.