Our Mission

Our mission is to improve health outcomes in infancy, childhood, adolescence, pregnancy, and postpartum among those who are impacted by or living with HIV by evaluating novel treatments and interventions for HIV, tuberculosis, and other related complications.

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IMPAACT 2034 Results Presented at 2025 Union World Conference on Lung Health

The International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network shared new interim data from IMPAACT 2034 today at the 2025 Union World Conference on Lung Health demonstrating that a single dose of pretomanid was safe, well-tolerated, and achieved pharmacokinetic (PK) exposures comparable to adults in female children with rifampicin-resistant tuberculosis.

IMPAACT 2034 Results Presented at 2025 Union World Lung Health Conference

News

November 2025

Meetings

IMPAACT 2034 Results Presented at 2025 Union World Conference on Lung Health

October 2025

Meetings

IMPAACT at IAS 2025 and HIV Pediatrics Workshop 2025

IMPAACT P1115 Results Published in The Lancet HIV

September 2025

Announcements

Four Children Experience HIV Remission: IMPAACT P1115 Results Published in The Lancet HIV

Research Areas

The IMPAACT Network is committed to conducting high-quality clinical trials to support our mission globally. Our research agenda includes four scientific specific aims.

Cure & Immunotherapy

Brain & Mental Health

Therapeutics

Tuberculosis

Studies

active studies

The IMPAACT Network is always working on many studies at one time in the areas of treatment, tuberculosis, ART-free remission, and complications.

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Study Snapshot

This document highlights major steps in protocol implementation and gives a quick look at accrual for each study. It is updated monthly.

Submit Study Proposals

Proposals for new IMPAACT studies may be submitted by internal or external investigators in the form of a concept sheet any time.

IMPAACT Community Engagement

Community participation and engagement are critical in the conduct of scientific research. There is mutual benefit to communities and researchers when both parties work together throughout the scientific research process. In the IMPAACT Network, community participation occurs throughout the network, community and site levels through various mechanisms that include representation on the network committees, protocols teams and cross network community activities.

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