Our Mission

Our mission is to improve health outcomes in infancy, childhood, adolescence, pregnancy, and postpartum among those who are impacted by or living with HIV by evaluating novel treatments and interventions for HIV, tuberculosis, and other related complications.

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Four Children Experience HIV Remission: IMPAACT P1115 Results Published in The Lancet HIV

The International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network is proud to announce the publication of results from P1115 in The Lancet HIV. P1115 is a Phase I/II, multi-center, proof-of-concept study that explores the effects of early intensive antiretroviral therapy on achieving HIV remission in neonates.

News

October 2025

Meetings

IMPAACT at IAS 2025 and HIV Pediatrics Workshop 2025

September 2025

Announcements

Four Children Experience HIV Remission: IMPAACT P1115 Results Published in The Lancet HIV

March 2025

Announcements

IMPAACT 2017 (MOCHA) Data Supports European Commission’s Authorization of Vocabria and Rekambys in Adolescents

Research Areas

The IMPAACT Network is committed to conducting high-quality clinical trials to support our mission globally. Our research agenda includes four scientific specific aims.

Cure & Immunotherapy

Brain & Mental Health

Therapeutics

Tuberculosis

Studies

active studies

The IMPAACT Network is always working on many studies at one time in the areas of treatment, tuberculosis, ART-free remission, and complications.

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Study Snapshot

This document highlights major steps in protocol implementation and gives a quick look at accrual for each study. It is updated monthly.

Submit Study Proposals

Proposals for new IMPAACT studies may be submitted by internal or external investigators in the form of a concept sheet any time.

IMPAACT Community Engagement

Community participation and engagement are critical in the conduct of scientific research. There is mutual benefit to communities and researchers when both parties work together throughout the scientific research process. In the IMPAACT Network, community participation occurs throughout the network, community and site levels through various mechanisms that include representation on the network committees, protocols teams and cross network community activities.

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