2019 Conference on Retroviruses and Opportunistic Infections (CROI)

Protocol

Title

Authors

Presentation Type

Tuesday, 5 March


P1081


Randomized trial of raltegravir-ART vs. efavirenz-ART when initiated during pregnancy


Mirochnick M, Shapiro DE, Morrison L, Frenkel L, Chakhtoura N, Siberry GK, Best B, Cruz MLS, Mmbaga BT, Pilotto JHS, Violari A, Prommas S, Joao E, for the NICHD P1081 Protocol Team


Oral presentation,
Room 6C,
10:00 AM – 12:00 PM


HPTN 046


Maternal HBV viremia is associated with adverse infant outcomes in HIV/HBV women


Bhattacharya D, Guo R, Tseng C, Emel L, Sun R, Chiu S, Stranix-Chibanda L, Chipato T, Mohtashemi NZ, Kintu K, Manji KP, Moodley D, Thio C, Maldonado Y, Currier J


Oral presentation,
Room 6C,
10:00 AM – 12:00 PM


P1112


Safety and pharmacokinetics of monoclonal antibody VRC01LS in HIV-exposed newborns


McFarland EJ, Cunningham CK, Capparelli EV, Muresan P, Smith E, Perlowski C, Morrison L, Morgan P, McDermott AB, Hazra R, Mascola JR, Graham B


Oral presentation,
Room 6C,
10:00 AM – 12:00 PM


PROMISE 1077BF


Preterm birth among women with ultrasound-based gestational dating in PROMISE 1077BF


Venkatesh KK, Farhad M, Fenton T, Moodley D, Naik S, Nakabiito C, Fairlie L, Makanani B, Saidi F, Chipato T, McIntyre J, Fowler MG, Chi BH, Stringer JSA, for the PROMISE 1077BF team


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM

Wednesday, 6 March


Lab


Entry kinetics of globally representative and vertically transmitted HIV envelopes


Webb NE, Tobin N, Aldrovandi GM


Poster presentation and themed discussion,
Room 606-609,
1:30 PM – 2:30 PM


Lab/
PACTG 338 and 377


Genomics links autophagy with neurocognitive impairment in HIV-infected children


Spector SA, Brummel SS, Singh KK, Kim J, Frazer KA, Nichols S, Seage III GR, Williams P, Van Dyke RB, Harismendy O, Trout RN


Poster presentation and themed discussion,
Room 6E,
1:30 PM – 2:30 PM


P1072 and
NWCS 612


Differences in gut microbial diversity in HIV infected vs exposed, uninfected infants


Koay WLA, Koh H, Bwakura-Dangarembizi M, Levin MJ, Weinberg A, Zhao N, Persaud D


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


Lab


Joint effects of HIV and obesity on the microbiome of young men who have sex with men


Cook RR, Fulcher JA, Tobin NH, Li F, Lee D, Javanbakht M, Brookmeyer R, Shoptaw S, Bolan R, Woodward C, Zabih S, Aldrovandi GM, Gorbach PM


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


Lab


Rectal microbiome alterations associated with TDF/FTC for pre-exposure prophylaxis


Fulcher JA, Li F, Cook RR, Zabih S, Woodward C, Louie A, Okochi H, Tobin NH, Gandhi M, Shoptaw S, Gorbach PM, Aldrovandi GM


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


PROMISE 1077BF/FF


HIV drug resistance at perinatal transmission and accumulation during breastfeeding


Boyce CL, Beck IA, Sils T, Ko D, Wong-on-Wing A, Styrchak S, DeMarrais P, Tierney C, Stranix-Chibanda L, Taha TE, Owor M, Fowler MG, Frenkel LM, for the Promoting Maternal and Infant Survival Everywhere trial (PROMISE) Study Team


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


P1115


Virologic response to very early ART in neonates with in utero HIV: IMPAACT P1115


Persaud D, Chadwick EG, Tierney C, Nelson B, Cotton M, Coletti A, Ruel T, Bwakura-Dangarembizi M, Mallewa M, Naidoo K, Reding C, Hazra R, Jean-Philippe P, Bryson Y, and the IMPAACT P1115 Team


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM

Thursday, 7 March


PROMISE 1077BF


Tenofovir hair levels rise over the postpartum period and highly predict viral loads


Murnane PM, Bacchetti P, Currier JS, Brummel S, Okochi H, Phung N, Kuncze K, Hoffman R, Nematadzira T, Soko D, Owor M, Saidi F, Flynn PM, Fowler MG, Gandhi M


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


PROMISE


Evaluation of guidelines for VL monitoring in pregnancy & breastfeeding: a simulation


Lesosky M, Raboud JM, Glass T, Brummel SS, Ciaranello AL, Currier JS, Essajee S, Havlir DV, Koss CA, Ogwu A, Shapiro RL, Abrams EJ, Myer L


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


P1078


Pregnancy associated with decreased serum isoniazid levels in women living with HIV


Gausi K, Denti P, Norman J, Wallis C, Onyango-Makumbi C, Chipato T, Theron G, Bradford S, Costello D, Browning N, Chakhtoura N, Weinberg A, Montepiedra G, Gupta A, and the IMPAACT P1078 (TB APPRISE) Study Group Team


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


P1093


PK and 4-week outcomes of dolutegravir dispersible tablets in HIV-infected children


Ruel T, Acosta E, Singh R, Alvero C, George K, Popson S, Bartlett M, Buchanan A, Brothers C, Koech L, Vhembo T, Hazra R, Townley E, Wiznia A, and the P1093 team


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM


HPTN 046


Extended prophylaxis with nevirapine does not affect growth in HIV-exposed infants


Onyango-Makumbi C, Mwiru RS, Owora AH, Mwatha A, Young AM, Moodley D, Coovadia HM, Stranix-Chibanda L, Manji K, Maldonado Y, Richardson P, Andrew P, George K, Fawzi W, Fowler MG


Poster presentation,
Poster Hall – 4EF,
2:30 PM – 4:30 PM