News from CROI 2024
Researchers from the IMPAACT Network presented data during three oral and twelve poster presentations at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI), held from 3 to 6 March 2024 in Denver, Colorado, USA.
Presentations and posters from the IMPAACT Network are listed below. Digital copies of presentations and posters will be hyperlinked when available. For the full conference program, visit the CROI website.
Press Releases
Oral & Poster Presentations
Oral Presentations
Below are oral presentations given during CROI 2024 listed by title. When digital copies are available, they will be hyperlinked.
Long-Acting Cabotegravir Plus Rilpivirine in Adolescents with HIV: Week 24 IMPAACT 2017 Study
PDF: Long-Acting Cabotegravir Plus Rilpivirine in Adolescents with HIV: Week 24 IMPAACT 2017 Study
Protocol: IMPAACT 2017/ MOCHA
Authors: Gaur A, Capparelli E, Baltrusaitis K, Marzinke M, Harrington C, McCoig C, Crauwels H, Townley E, Moye J, Buisson S, Violari A, Ounchanum P, Krotje C, Bolton Moore C, IMPAACT 2017 Team
Hypertension in a Randomized Trial of DTG vs EFV-based ART in Pregnant and Postpartum Women
PDF: Hypertension in a Randomized Trial of DTG vs EFV-based ART in Pregnant and Postpartum Women
Protocol: IMPAACT 2010/VESTED
Authors: Hoffman R, Brummel S, Pinilla M, Malonga G, Chinula L, Hanley S, Stranix-Chibanda L, Machado ES, Naik S, McCarthy K, Krotje C, Jean-Philippe P, Sax P, Currier J, Lockman S
ART-free HIV-1 Remission in Very Early Treated Children: Results from IMPAACT P1115
Protocol: IMPAACT P1115
Authors: Persaud D, Coletti A, Nelson BS, Jao J, Capparelli E, Costello D, Tierney C, Kekitiinwa AR, Nematadzira T, Njau BN, Moye J, Jean-Philippe P, Bryson Y, Chadwick EG, for the IMPAACT P1115 Study Team
Poster Presentations
Below are poster presentations given during CROI 2024 listed by protocol/team. When digital copies are available, they will be hyperlinked.
PROMISE 1077BF/FF
1077BF: Breast Milk Reservoir, Tenofovir levels and HIV Transmission Among Breastfeeding Mothers
Owor M, DeMarrais P, Baltrusaitis K, Frenkel LM, Best B, Stranix Chibanda L, Mallewa M, Kamthunzi P, Moodley D, Violari A, Chipato T, Kakayi B, Bhosale R, Fowler MG
IMPAACT Laboratory
Metabolomic Perturbations of Tryptophan and Arginine Metabolites in the Breast Milk of Women With HIV
Tobin NH, Li F, Ferbas KG, Sleasman JW, Kuhn L, Aldrovandi GM, for the ZEBS study team
P1078/TB APPRISE (NWCS 631)
Pharmacokinetics of Isoniazid Metabolites During Pregnancy and Postpartum
Klein B, Wei Z, Nerguizian D, Gupta A, Weinberg A, Montepiedra G, Morrow M, MaWhinney S, Musoke P, Auripibul L, Masheto G, Bushman L, Anderson PL, Brooks KM
IMPAACT 2019 + P1093
A Single Once Daily ABC/DTG/3TC Tablet Predicts Safe and Effective Exposures in Children 3 to <6kg
Chandasana H, Brooks K, Buchanan AM, Tan L, Mujuru H, Colbers A, Hopking J, Cuiffa M, McKenna M, Wiznia A, Brummel S, Bekker A, Cressey T, Rabie H
Population Pharmacokinetics ABC/DTG/3TC FDC to Support Dosing in Peds with HIV-1 (IMPAACT 2019)
Chandasana H, van Dijkman S, Mehta R, Bush M, Rabie H, Flynn P, Cressey TR, Acosta E, Brooks KM, for the IMPAACT 2019 Protocol Team
Dolutegravir and Growth in Pediatric Populations With HIV-1: IMPAACT P1093 and IMPAACT 2019
McKenna M, Lulic Z, Buchanan AM, Brothers C, Tan L, Wang M, Brummel S, Ziemba L, Ruel T, Flynn PM, Rabie H, Wiznia A
IMPAACT 2010/VESTED
Breast Milk Transfer and Infant Exposures to DTG, TAF, and TFV: Results from IMPAACT 2010/VESTED
Nguyen T, Chae JW, Ziemba L, Coletti A, Knowles K, Johnston B, Jean-Philippe P, Mhembere T, Chawana T, Wabwire D, Korutaro V, Lockman S, Chinula L, Momper J, on behalf of the IMPAACT 2010/VESTED Protocol Team
IMPAACT 2017/MOCHA
Cabotegravir PopPK Analysis of Adults & Adolescents Living with HIV or at Risk for HIV Receiving PrEP
Lin YW, Cheung SYA, Deprez I, Ford S, Collins J, McCoig C, Harrington C, Gaur A, Bolton C, Stranix-Chibanda L, Hosek S, Marzinke M, Best B, Capparelli E, and IMPAACT 2017 team
IMPAACT 2017 Adolescent/Parent Experiences with LA Cabotegravir Plus Rilpivirine for HIV Treatment
Lowenthal ED, Chapman JC, Zapata Vaca M, Ward S, Milligan R, Camacho-Gonzalez A, Masheto G, McCoig C, Ace A, Van Solingen R, Yin D, Buisson S, Bolton C, Gaur A, IMPAACT 2017 Team
IMPAACT P1115
Proviral Landscape in Neonates with In Utero HIV-1 on Very Early ART in IMPAACT P1115
Bekka SK, Khetan P, Liu Y, Dhummakupt A, Nelson BS, Tierney C, Chadwick E, Jao J, Bryson Y, Coletti A, Nicodimus N, Stranix-Chibanda L, Lee GQ, Ray S, Persaud D
DR 835 (PACTG 300, 353, 356, 358, and 386; IMPAACT P1069 and P1106; and Early Infant HIV Treatment in Botswana study)
Lamivudine (3TC) Dosing for Preterm Neonates Exposed to HIV
Bekker A, Capparelli EV, Mirochnick M, Clarke DF, Cotton MF, Shapiro R, McCarthy K, Moye J, Violari A, Chokephaibulkit K, Abrams E, Penazzato M, Ruel T, Cressey TR
IMPAACT 2009
Maternal and Pregnancy Outcomes in Women Initiating and Declining PrEP in Pregnancy: IMPAACT 2009
Chi BH, Kacanek D, Brown E, Amico KR, Huang S, Nematadzira T, Horne E, Nakabiito C, Mambiya SK, Korutaro V, Johnson B, Rooney JF, Spiegel H, Stranix-Chibanda L, on behalf of the IMPAACT 2009 team