IMPAACT 2020: Phase II Study of Shortened Oral Treatment for Multidrug-Resistant Tuberculosis in Children (SMaRT Kids)
| Study Status | Study Restriction |
|---|---|
In Development |
Non-US |
What is IMPAACT 2020?
IMPAACT 2020 is a Phase II, two-arm, open-label study of children with and without HIV who are less than 15 years of age with confirmed or probable tuberculosis (TB) that is resistant to rifampicin. The study is designed to characterize the safety, tolerability, and treatment outcomes of an all-oral, six-month novel regimen. The study will also include a mixed-methods, socio-behavioral component to assess priorities and preferences for TB treatment among a subset of participants and caregivers.
Sites where the study is implemented:
| CRS ID | Site Name | City | Country | |
|---|---|---|---|---|
| Site Selection in progress. | ||||
Study contacts:
Study Chair: Anthony Garcia-Prats |
Study Vice-Chair: Anneke Hesseling |
Study Vice-Chair: Simon Schaaf |
DAIDS Medical Officer: Tafadzwa Kasambira |
DAIDS Medical Officer: Hans Spiegel |
NICHD Medical Officer: Jack Moye |
Clinical Trials Specialist: Elizabeth Greene |
Clinical Trials Specialist: Katie McCarthy |
Clinical Trials Specialist: Nicole Montañez |
Community Program Manager: Jonathan Lucas |
Data Manager: Kira Bacon |
Data Manager: Mattie Bartlett |
Data Manager: Amanda Golner |
Investigator: Kelly Dooley |
Investigator: Pauline Howell |
Investigator: Carolyne Onyango |
Investigator: Vanessa Rouzier |
Investigator: James Seddon |
Laboratory Data Manager (LDM): Rachel Bowman |
Laboratory Data Manager (LDM): Kyle Whitson |
Laboratory Specialist: William Murtaugh |
Laboratory Specialist: Samantha Solomon |
Laboratory Technologist: Vandana Kulkarni |
Protocol Pharmacist: Oladapo Alli |
Protocol Pharmacist: Justine Beck |
Statistician: Soyeon Kim |
Statistician: Leavitt Morrison |
TB Civil Society Advocacy Representative: Lindsay McKenna |
Westat Representative: Marsha Johnson |
Microbiologist: Anne-Marie Demers |
Microbiologist: Willy Ssengooba |
Pharmacometrician: Mats Karlsson |
Pharmacometrician: Elin Svensson |