P1026S / PK in Pregnancy

P1026s is a Phase IV, prospective pharmacokinetic (PK) study of selected ARV drugs currently used in the clinical care of HIV-infected pregnant women during pregnancy and postpartum.  This study is designed to evaluate the following: the pharmacokinetics of antiretroviral medicines when used alone or co-administered with tuberculosis medicines during pregnancy; the pharmacokinetic parameters of lopinavir/ritonavir and atazanavir/ritonavir/tenofovir in women postpartum before and after starting hormonal contraceptives; and the concentrations of ethinyl estradiol, etonogestrel and other progestins in women using hormonal contraceptives and protease inhibitors.