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IMPAACT 2015

Evaluation of the HIV-1 Reservoir in the Central Nervous System
of Perinatally-Infected Youth and Young Adults with Cognitive Impairment

Study Status

Concluded

DAIDS Number

35123

IND Number

non-IND

Clinical Trials Link

Primary Protocol Team Members

Thor Wagner Study Co-Chair
Ann Chahroudi Study Co-Chair
Hans Spiegel DAIDS Medical Officer
Eric Lorenzo NICHD Medical Officer

Summary

IMPAACT 2015 is a cross-sectional study that will investigate the central nervous system reservoir in perinatally HIV-infected adolescents and young adults on effective antiretroviral therapy with neurocognitive impairment. The study will assess the frequency with which HIV is detected in the cerebral spinal fluid (CSF) in this population and assess whether detectable HIV in the CSF correlates with markers of inflammation and neuronal injury.

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