IMPAACT 2046 / UPLIFT Study

IMPAACT 2046/UPLIFT (Understanding Parental Lactation and Infant Feeding decisions Tailored to people with HIV) is a multi-site, mixed-methods, observational cohort study. The purpose of the study is to explore infant feeding preferences, practices, and outcomes among mothers and other parents with HIV (MoPWH) in the United States. It will employ both qualitative and quantitative research methods to address existing knowledge gaps and to understand the clinical, behavioral, and social factors influencing infant feeding decisions. As part of the study’s mixed method approach, a longitudinal cohort study of MoPWH and their infants will be established. The study also aims to pilot a national registry of breast/chest-feeding individuals living with HIV in the United States. The study will be open to US sites only in accordance with its CDC grant funding specifications.