Manuscripts

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Showing 1551 manuscripts.

Population Pharmacokinetic Modeling of Dolutegravir to Optimize Pediatric Dosing in HIV-1-Infected Infants, Children, and Adolescents

Theodore Ruel, David Burger, Andrew Wiznia, Edward P. Acosta, Lee Fairlie, Rajendra Singh, Lucy Koech, IMPAACT P1093 and ODYSSEY (PENTA 20) Study Teams, Mutsawashe Bwakura-Dangarembizi, Hilda Mujuru, Adeodata R. Kekitiinwa, Cissy M. Kityo, Carmelita Alvero, Hardik Chandasana, Mona Farhad, Mita Thapar, Rohan Hazra, Siobhan Hayes, Ellen Townley, Mark Baker, Ann Buchanan, Diana M Gibb, Pauline Bollen, Anna Turkova, Hylke Waalewijn, Deborah Ford, Angela Colbers. Population Pharmacokinetic Modeling of Dolutegravir to Optimize Pediatric Dosing in HIV-1-Infected Infants, Children, and Adolescents. Clinical Pharmacokinetics. 62: 1445-1459. PMID: 37603217

Journal

Clinical Pharmacokinetics

Study

P1093

Impact of Genetic Variants in ABCG2, NR1I2 and UGT1A1 on the Pharmacokinetics of Dolutegravir in Children

Audrey Chang, Andrew Wiznia, Theodore D. Ruel, Edward P. Acosta, IMPAACT 1093 Team, Stephen A. Spector, Sean S. Brummel. Impact of Genetic Variants in ABCG2, NR1I2 and UGT1A1 on the Pharmacokinetics of Dolutegravir in Children. Journal of Acquired Immune Deficiency Syndromes. 95: doi: 10.1097/QAI.000000000000335. PMID: 38180896

Journal

Journal of Acquired Immune Deficiency Syndromes

Study

P1093

Bridging Dolutegravir Clinical Viral Response Across Doses and Formulations Using Model-Based Exposure-Response Analysis in Pediatrics

Ellen Townley, Rohan Hazra, Kathy George, Cindy Vavro, Theodore Ruel, Edward Acosta, IMPAACT P1093 Team, Hardik Chandasana, Rajendra Singh, Annie Buchanan, Cynthia Brothers, Andy Wiznia, Mattie Bartlett, Stephanie Popson. Bridging Dolutegravir Clinical Viral Response Across Doses and Formulations Using Model-Based Exposure-Response Analysis in Pediatrics. PMID: 38768443

Study

P1093

Prevalence of detectable HIV-DNA and HIV-RNA in cerebrospinal fluid of youth with perinatal HIV and impaired cognition on antiretroviral therapy

Murli Purswani, Allison Bearden, Andrew Wiznia, Allison Agwu, Thor A. Wagner, Ellen G. Chadwick, Camlin Tierney, Douglas Richman, Sharon Huang, Monica Gandhi, Sharon Nichols, Patrick Mehta, Kathleen M. Malee, Bernard Macatangay, Nicole A. Montañez, Stephen A. Spector, Anne Coletti, Serena Spudich, Hans ML Spiegel, Deborah Persaud, Chelsea Krotje, Ann Chahroudi, Frederic Bone, IMPAACT 2015 Protocol Team, Megan Wilkins, Lisa Abuogi. Prevalence of detectable HIV-DNA and HIV-RNA in cerebrospinal fluid of youth with perinatal HIV and impaired cognition on antiretroviral therapy. AIDS. 38: 1494-1504. PMID: 38814693

Journal

AIDS

Study

IMPAACT 2015

Population Pharmacokinetic Modeling of Abacavir/Dolutegravir/Lamivudine to Support a Fixed-Dose Combination in Children with HIV-1

Rashmi Mehta, Mark Bush, Helena Rabie, Patricia Flynn, Tim R. Cressey, Edward P. Acosta, Kristina M. Brooks, IMPAACT 2019 Study Team, Hardik Chandasana, Sven C. van Dijkman. Population Pharmacokinetic Modeling of Abacavir/Dolutegravir/Lamivudine to Support a Fixed-Dose Combination in Children with HIV-1. Infectious Diseases and Therapy. PMID: 38961048

Journal

Infectious Diseases and Therapy

Study

IMPAACT 2019

Effects of preterm birth, maternal ART and breastfeeding on 24-month infant HIV-free survival in a randomized trial

Mauricio Pinilla, Katie S. McCarthy, Lameck Chinula, Renee Browning, Maxensia Owor, Lynne M. Mofenson, Avy Violari, Sean S. Brummel, Dhayendre Moodley, Mary Glenn Fowler, Lynda Stranix-Chibanda, PROMISE 1077BF/FF Team, Taguma Allen Matubu, Gift Tafadzwa Chareka, Gerhard Theron, Aarti Avinash Kinikar, Mwangelwa Mubiana-Mbewe, Lee Fairlie, Raziya Bobat, Blandina Theophil Mmbaga, Sufia Dadabhai, Patricia M. Flynn, Victoria B. Chou, Taha E. Taha. Effects of preterm birth, maternal ART and breastfeeding on 24-month infant HIV-free survival in a randomized trial. AIDS. PMID: 38427596

Journal

AIDS

Impact of HIV drug resistance mutations detected in women prior to antiretroviral therapy with efavirenz + tenofovir + lamivudine (or emtricitabine)

PROMISE Study Team, Ceejay L. Boyce, Tatiana Sils, Ross S. Milne, Jackson J. Wallner, Samantha R. Hardy, Daisy Ko, Annie Wong-On-Wing, Malia Mackey, Nikki Higa, Ingrid A. Beck, Sheila M. Styrchak, Patricia DeMarrais, Camlin Tierney, Mary G. Fowler, Lisa M. Frenkel. Impact of HIV drug resistance mutations detected in women prior to antiretroviral therapy with efavirenz + tenofovir + lamivudine (or emtricitabine). Lancet HIV.

Journal

Lancet HIV

Participant acceptability and clinician satisfaction of cognitive behavioural therapy and medication management algorithm compared with enhanced standard care for treatment of depression among youth with HIV

Chelsea Krotje, Kevin Knowles, Sarah Buisson, Lauren Bergam, Jaime Deville, Susan Gillespie, Melissa Shikora, Ellen Townley, David E. Shapiro, Larry K. Brown, Emily A. Barr, Kristin Baltrusaitis, Betsy D. Kennard, Graham J. Emslie. Participant acceptability and clinician satisfaction of cognitive behavioural therapy and medication management algorithm compared with enhanced standard care for treatment of depression among youth with HIV. Journal of Child & Adolescent Mental Health. 1-16. PMID: 39550758

Journal

Journal of Child & Adolescent Mental Health

Study

IMPAACT 2002

Lipid and glucose profiles in pregnant women with HIV on tenofovir-based antiretroviral therapy

Ifeanyi Ezebialu, Violet Korutaro, Deo Wabwire, Allen Matubu, Tapiwa Mbengeranwa, Nahida Chakhtoura, Lameck Chinula, Katie McCarthy, Kevin Knowles, Chelsea Krotje, MacRae F Linton, Ahizechukwu Eke, Kelly Dooley, Sean Brummel, Paul Sax, Muktar H Aliyu, Todd Brown, Lynda Stranix-Chibanda, Shahin Lockman, George Uchenna Eleje, IMPAACT 2010/VESTED Study Team. Lipid and glucose profiles in pregnant women with HIV on tenofovir-based antiretroviral therapy. Clinical Infectious Diseases. ciae441PMID: 39219495

Journal

Clinical Infectious Diseases

Study

IMPAACT 2010