2023 IMPAACT Annual Meeting
The hybrid event brought together IMPAACT Network leadership, investigators, research site staff, community advocates, and network affiliates to discuss the network's scientific agenda and explore innovative approaches to future research. Representing 47 research sites across 12 countries, nearly 1,000 people attended in person or virtually. The six-day meeting was filled with engaging presentations, collaborative sessions, and networking activities, providing an opportunity to share lessons learned, inspire implementation strategies, and sharpen operational best practices.
Plenary recordings and presentations are available below:
DAIDS Director Dr. Carl Dieffenbach (left) with IMPAACT Network Chair Dr. Sharon Nachman (right)
Monday, 23 October 2023
Community Advisory Board Meeting – Watch Recording
- State of the Network: The Way Forward for IMPAACT – Dr. Sharon Nachman
- Best Practices for Engaging Parents/Caregivers – Dr. Dorothy Dow
- Inclusion of Pregnant People Earlier in HIV/TB Treatment Research: The Great Debate – Dr. Mark Mirochnick
- Socio-Behavioral Research: The Why That Compliments the What – Dr. Rivet Amico
- Best Practices for Liaising with Non-Study Medical Care Providers – Dr. Patricia Nahirya Ntege
- Broadly Neutralizing Antibodies: The HIV Treatment Research Agenda – Dr. Betsy McFarland
- Building an Effective Youth Community Advisory Board – Emanueli Msuya
- Considerations for Establishing a Welcoming Clinic for Children – Cissy Ssuuna
- Preparing for Clinical Trials Results Dissemination – Ernest Moseki
- Complex Comorbidity: HIV and Tuberculosis, A Global Update – Dr. Amita Gupta
- Addressing Intimate Partner Violence in HIV Research – Dr. Kenneth Ngure
Therapeutics (formally known as Treatment) Scientific Committee
- Welcome and Update on New “Therapeutics” Agenda – Ted Ruel
- Update from CS 5035: Pharmacokinetics of Benzathine Penicillin and Ceftriaxone in Pregnancy – Jason Zucker
- Empiric Treatment for Cytomegalovirus (CMV) and Tuberculosis (TB) in Children with HIV and Pneumonia – Pablo Rojo
- Overview of DTG Global Rollout Among Pregnant People and Children – George Siberry
- Patient Perspectives on the DTG Rollout – Thabo Makete & Aisha Nakitto
- Increasing Second-Line ART Options for Children with HIV in Africa: Week-96 Efficacy/Safety Results of the CHAPAS-4 Randomised Trial – Mutsa Bwakura-Dangarembizi
- What have we learned about DTG resistance in from the ODYSSEY trial? – Alasdair Bamford
- Frequency and Mechanisms of DTG Resistance: Lessons from P1093 and IMPAACT 2010/VESTED – Ceejay Boyce
Tuesday, 24 October 2023
Plenary I – Watch Recording
- Welcome – Patricia Flynn, MD, and Philippa Musoke, MBChB, PhD
- Fireside Discussion – Carl Dieffenbach, PhD & Sharon Nachman, MD
- State of the Network – Sharon Nachman, MD
- Global Pediatric HIV Epidemic: Progress, Gaps & Future Research Priorities – George Siberry, MD, MPH, FPIDS
- Panel Discussion – Moderated by Elaine Abrams, MD
- George Siberry, MD, MPH, FPIDS
- Hilary Wolf, MD
- Bill Kapogiannis, MD, FIDSA
- Philippa Musoke, MD, PhD
- Grace John-Stewart, MD, PhD
- Maternal HIV Infection and Its Association with Milk Metabolites: Insights and Implications – Grace Aldrovandi, MD
Brain and Mental Health (formally known as Complications) Scientific Committee
- Welcome and Committee Introduction – Jackie Hoare
- Brain health complications in women with HIV: where do we go from here? – Leah Rubin
- Possible Roles of Extracellular Condensates in HIV Persistence – Chioma Okeoma
- Updates on IMPAACT 2016: Evaluating a Group-Based Intervention to Improve Mental Health and ART Adherence Among Youth Living with HIV in Low Resource Settings – Geri Donenberg and Dorothy Dow
- ICAB Presentation – Gwynneth Hendricks and Angie Partap
- Panel Discussion: Future directions for treatment of depression and anxiety in adolescents living with HIV
- Tackling the Wicked Problem of Depression in Adolescents – Kathryn Cullen
- Novel Sleep-Circadian Treatment Approaches for Depression in Children and Adolescents Living with HIV – Adriane Soehner
- Mindfulness Based Real-Time Neurofeedback: A Novel Personalized Network-Based Intervention – Susan Whitfield-Gabrieli
Wednesday, 25 October 2023
Plenary II – Recording unavailable
- Welcome - Moherndran Archary, MBChB, PhD & Megan McHenry, MD
- The Power of Connected Clinical Teams: from Loneliness to Belonging - Jacqueline Hoare, MPhil, PhD
- Going Long – Use of PK/PD Modeling and Simulation for Long-Acting ARVs - Edmund Capparelli, PharmD
- Lessons Learned from Dolutegravir Pediatric Model Informed Drug Development - Hardik Chandasana, PhD
- Long-Acting Antiretrovirals in Adolescents: Notes from IMPAACT 2017 (MOCHA Study) - Carolyn Bolton Moore, MBBCh, MSc; Elizabeth Lowenthal, MD; Aditya Gaur, MD
- New/Updated DMC Systems/Initiatives - Marlene Cooper, MS
- Putting Estimands into Practice - Kristin Baltrusaitis, PhD
- Statistical Considerations for Studies in Pregnancy and Postpartum - Sean Brummel, PhD
- Network Awards - Philippa Musoke, MBChB, PhD
DAIDS Remote Site Monitoring Visits
Friday, 27 October 2023
Tuberculosis Scientific Community
- Tuberculosis Scientific Committee Update – Anneke Hesseling and Amita Gupta
- Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients – Amita Gupta, MD
- Novel Approaches to Imaging in Paediatric TB: Application to Clinical Trials – Megan Palmer, MD
- Rifapentine in High Doses in Pregnancy with TB – Yael Hirsch-Moverman, PhD, MPH and Jyoti Mathad, MD, MS
- MDR-TB drugs in pregnancy – Jennifer Hughes, MD
Announcing 2024 and 2025 IMPAACT Annual Meetings
Join us 22-27 September 2024 and 7-12 September 2025 at the Crystal Gateway Marriott in Arlington, Virginia for the next IMPAACT Annual Meetings!
